GeneticsbioRxivPreprint
CRISPR tiling deletion screens reveal functional enhancers of neuropsychiatric risk genes and allelic compensation effects (ACE) on transcription
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University of California, San FranciscoORCID 0000-0003-0032-1130Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Xingjie Ren, Han Kwang Yang, Jovia L. Nierenberg…·Yin Shen
This paper introduces PRIME, a high-throughput prime editing screen that identifies functional DNA variants in the human genome with base-pair resolution.
Xingjie Ren, Mengchi Wang, Bingkun Li…·Yin Shen
CRISPRpath enables parallel characterization of cis-regulatory elements for multiple genes in a pathway, identifying functional enhancers and distinguishing their impact on gene expression.