Author

Han Kwang Yang

University of California, San FranciscoORCID 0000-0002-9150-8146Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant effect prediction· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Cooper BeamaniD· 2 shared Xingjie ReniD· 2 shared Yin SheniD· 2 shared Yun LiiD· 2 shared Bin LiiD· 1 shared Bing ReniD· 1 shared Elad ZiviD· 1 shared Ian Richard JonesiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Cooper BeamanORCID

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2 papers

Recent·Most cited

High throughput PRIME editing screens identify functional DNA variants in the human genome

Xingjie Ren, Han Kwang Yang, Jovia L. Nierenberg, Yifan Sun, Jiawen Carmen Chen, Cooper Beaman, Thu Huong Pham, Mai Nobuhara, Maya Asami Takagi, Vivek Narayan, Yun Li, Elad Ziv, Yin Shen

This paper introduces PRIME, a high-throughput prime editing screen that identifies functional DNA variants in the human genome with base-pair resolution.

Molecular Cell · Dec 1, 2023Peer-reviewedGenomics

Functional characterization of gene regulatory elements and neuropsychiatric disease-associated risk loci in iPSCs and iPSC-derived neurons

Xiaoyu Yang, Ian Richard Jones, Poshen B. Chen, Han Kwang Yang, Xingjie Ren, Lina Zheng, Bin Li, Yang Eric Li, Quan Sun, Jia Wen, Cooper Beaman, Xiekui Cui, Yun Li, Wei Wang, Ming Hu, , Yin Shen

The paper identifies functional CREs in iPSCs and neurons and links them to neuropsychiatric disease risk variants.

bioRxiv · Aug 30, 2023 · PreprintGenetics