GeneticsbioRxivPreprint
CRISPR tiling deletion screens reveal functional enhancers of neuropsychiatric risk genes and allelic compensation effects (ACE) on transcription
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University of California, San FranciscoORCID 0000-0002-8626-3594Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Xingjie Ren, Mengchi Wang, Bingkun Li…·Yin Shen
CRISPRpath enables parallel characterization of cis-regulatory elements for multiple genes in a pathway, identifying functional enhancers and distinguishing their impact on gene expression.
Michael Song, Mark-Phillip Pebworth, Xiaoyu Yang…·Yin Shen
This study characterizes 3D epigenomic landscapes during human corticogenesis, revealing chromatin looping and super interactive promoters involved in lineage-specific gene regulation.