BiophysicsbioRxivPreprint
Allosteric Control and Glycan Shielding Adaptations in the SARS-CoV-2 Spike from Early to Peak Virulence
Srirupa Chakraborty, Kien Nguyen, Mingfei Zhao, Sandrasegaram Gnanakaran
This study analyzes structural changes in the SARS-CoV-2 Spike protein between D614G and Delta variants using molecular dynamics simulations to identify allosteric and glycan shielding adaptations affecting virulence and immune evasion.
DOI 10.1101/2025.03.11.642723