Christine M. Dunham

The paper uses a simulation model to show how ribosome structure and molecular sterics guide tmRNA translocation during trans-translation.

This paper characterizes SRLase1, an RNase toxin that cleaves the sarcin-ricin loop of 23S rRNA by repurposing EF-Tu, revealing a new mechanism of ribosome inhibition.

This study identifies bL27's role in preventing tmRNA from interfering with protein synthesis during trans-translation in bacteria.

This study determines the cryo-EM structure of the RsmI-30S complex and reveals how RsmI recognizes and modifies the 16S rRNA C1402 nucleotide.

The paper introduces the RAD method to quantitatively describe subunit rotations in ribosomes and applies it to analyze ribosome structures across organisms.