Andrea Stojakovic

The paper assesses a novel mitochondrial complex I inhibitor, C458, in vitro and in vivo, showing it protects against Aβ toxicity, improves brain energetics, and reduces inflammation in Alzheimer's disease models.

This study examines how prior nicotine and alcohol exposure affects amphetamine reward in adolescent and adult mice, finding age-dependent differences in dopamine receptor expression and reward behavior.

The paper shows that partial inhibition of mitochondrial complex I protects against neurodegeneration in Alzheimer's mice by improving energy homeostasis, synaptic function, and reducing inflammation.

This study shows that inhibiting mitochondrial complex I with CP2 reduces pTau levels and improves cognitive and metabolic function in 3xTg-AD mice.