Author

Venugopala Reddy Mekala

Baylor College of MedicineORCID 0000-0001-7193-3682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Akash R. BodaiD· 1 shared Chao ChengiD· 1 shared Christopher I. Amos· 1 shared Irfan N. BandeyiD· 1 shared Jason RoszikiD· 1 shared Jia WuiD· 1 shared Jianjun J. ZhangiD· 1 shared Jianrong LiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Akash R. BodaORCID

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2 papers

Recent·Most cited

BioinformaticsInternational Journal of CancerPeer-reviewedDec 16, 2025

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre-cancer lesions

Yupei Lin, Venugopala Reddy Mekala, Jianrong Li…·Chao Cheng

This study develops gene expression signatures from LUSC tumors to predict progression risk of precancerous lesions, finding they outperform genomic aberrations in prognosis and correlate with immune features.

1 citation

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintFeb 23, 2025

IL-1R1 Blockade Enhances CD40 Agonist-Mediated Immune Responses but Fails to Increase Efficacy or Mitigate Hepatotoxicity in Pancreatic Cancer

Akash R. Boda, Irfan N. Bandey, Saikat Chowdhury…·Manisha Singh

This study investigates the effect of IL-1R1 blockade on CD40 agonist therapy in PDAC, finding it does not improve efficacy and worsens liver toxicity.

1 citation

mouseexperimental assay

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