Author

Johannes Heimgärtner

Science for Life LaboratoryORCID 0000-0003-0059-9888Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Birthe MeinekeiD· 1 shared Lorenzo LafranchiiD· 1 shared Simon J. ElsässeriD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperSynthetic Biology

Birthe MeinekeORCID

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1 paper

Recent·Most cited

Synthetic BiologyACS Chemical BiologyPeer-reviewedSep 27, 2018

Methanomethylophilus alvus Mx1201 provides basis for mutual orthogonal pyrrolysyl tRNA/aminoacyl-tRNA synthetase pairs in mammalian cells

Birthe Meineke, Johannes Heimgärtner, Lorenzo Lafranchi, Simon J. Elsässer

The paper identifies a new pyrrolysyl tRNA/aminoacyl-tRNA synthetase pair from M. alvus Mx1201 that is orthogonal to Mma PylRS/PylT in mammalian cells, enabling site-specific ncAA incorporation via distinct stop codons.

85 citations

humanexperimental assay

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