Author

Seunghyun Ryu

University of Tennessee at KnoxvilleORCID 0000-0003-0089-7922Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Cong T. TrinhiD· 3 shared Caleb Walker· 2 shared David Dooley· 2 shared Richard J. GiannoneiD· 2 shared Bamin KhomamiiD· 1 shared Bindica Poudel· 1 shared Brian J. Mendoza· 1 shared Bruce S. DieniD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersSystems Biology

Cong T. TrinhORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintJul 15, 2024

Expanded Genome and Proteome Reallocation in a Novel, Robust Bacillus coagulans Capable of Utilizing Pentose and Hexose Sugars

David Dooley, Seunghyun Ryu, Richard J. Giannone…·Cong T. Trinh

This study characterizes a novel robust Bacillus coagulans strain capable of utilizing pentose and hexose sugars, revealing proteome reallocation and metabolic strategies for biomass hydrolysate utilization.

1 citation

bacteria (other)whole-genome sequencing

𝕏 PostBluesky

Systems BiologymSystemsPeer-reviewedOct 26, 2023

Proteomes Reveal Metabolic Capabilities of Yarrowia lipolytica for Biological Upcycling of Polyethylene into High-Value Chemicals

Caleb Walker, Max Mortensen, Bindica Poudel…·Cong T. Trinh

This study identifies how Yarrowia lipolytica metabolizes hydrocarbons and DP oil, revealing proteome reallocation for growth and chemical production, but also growth inhibition due to reduced protein biosynthesis.

17 citations

yeastproteomics

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Systems BiologybioRxivPreprintMar 17, 2022

Gene Co-expression Connectivity Predicts Gene Targets Underlying High Ionic Liquid Tolerance in Yarrowia lipolytica

Caleb Walker, Seunghyun Ryu, Sergio Garcia…·Cong T. Trinh

The paper introduces GeCCo to identify gene targets for high ionic liquid tolerance in Y. lipolytica and finds that GeCCo-selected genes, BRN1 and OYE2, enhance tolerance when overexpressed.

DOI 10.1101/2022.03.17.484694

yeastbulk RNA-seq

𝕏 PostBluesky