Author

Bruce S. Dien

Agricultural Research ServiceORCID 0000-0003-3863-6664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Cong T. TrinhiD· 2 shared Patricia J. Slininger· 2 shared Richard J. GiannoneiD· 2 shared Andrei Stecca SteindorffiD· 1 shared Caleb Walker· 1 shared Chris Todd HittingeriD· 1 shared Chu-I Yang· 1 shared Dana A. OpulenteiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersSystems Biology

Cong T. TrinhORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintAug 29, 2025

MAESTRO uncovers tandem paralog dynamics as a core driver of fungal stress adaptation

Ping-Hung Hsieh, Yusuke Sasaki, Chu-I Yang…·Yasuo Yoshikuni

MAESTRO identifies tandem paralog copy number variation as a key mechanism for stress adaptation in Pichia kudriavzevii, linking it to drug resistance and environmental tolerance.

3 citations

yeastGWAS summary statistics

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Systems BiologybioRxivPreprintJul 15, 2024

Expanded Genome and Proteome Reallocation in a Novel, Robust Bacillus coagulans Capable of Utilizing Pentose and Hexose Sugars

David Dooley, Seunghyun Ryu, Richard J. Giannone…·Cong T. Trinh

This study characterizes a novel robust Bacillus coagulans strain capable of utilizing pentose and hexose sugars, revealing proteome reallocation and metabolic strategies for biomass hydrolysate utilization.

1 citation

bacteria (other)whole-genome sequencing

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Systems BiologymSystemsPeer-reviewedAug 3, 2021

Exploring Proteomes of Robust Yarrowia lipolytica Isolates Cultivated in Biomass Hydrolysate Reveal Key Processes Impacting Mixed Sugar Utilization, Lipid Accumulation, and Degradation

Caleb Walker, Bruce S. Dien, Richard J. Giannone…·Cong T. Trinh

The paper analyzes genetic and proteomic differences between undomesticated and conventional Yarrowia lipolytica strains to understand lipid metabolism and sugar utilization in biomass hydrolysates.

30 citations

yeastproteomics

𝕏 PostBluesky