Kwang Pyo Kim

This study evaluates the quality and suitability of long-term stored tissues for multi-omics analyses, showing that while transcriptomic data show some changes, core gene expression and proteomic measurements remain reliable.

The paper identifies ITGA3B1 as a therapeutic target for metastatic bladder cancer using a phenotypic screening strategy and develops an ADC targeting this integrin complex, showing antitumor efficacy in preclinical models.

Vutiglabridin, a clinical-stage drug for obesity, shows neuroprotective effects in Parkinson's disease models by targeting mitochondrial PON2.