Synthetic BiologybioRxivPreprint
Targeting the ITGA3B1 Complex with A Novel Antibody-Drug Conjugate for Metastatic Bladder Cancer
Hyeryeon Jung, Junghyeon Lee, Eunhee G. Kim…·Kristine M. Kim
The paper identifies ITGA3B1 as a therapeutic target for metastatic bladder cancer using a phenotypic screening strategy and develops an ADC targeting this integrin complex, showing antitumor efficacy in preclinical models.
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