Author

Emrah Akkoyun

Sabancı ÜniversitesiORCID 0000-0003-0101-3551Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:machine learning (classical)· 1 Research Focus:variant effect prediction· 1

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Aylin BırcaniD· 1 shared Nurdan KuruiD· 1 shared Ogün AdebalıiD· 1 shared Onur DereliiD· 1 shared Öznur TaştaniD· 1 shared

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Recent·Most cited

BioinformaticsbioRxivPreprintJan 30, 2024

PHACTboost: A Phylogeny-aware Boosting Algorithm to Compute the Pathogenicity of Missense Mutations

Onur Dereli, Nurdan Kuru, Emrah Akkoyun…·Ogün Adebalı

PHACTboost improves missense variant pathogenicity prediction by integrating phylogenetic trees, multiple sequence alignments, and ancestral reconstruction, outperforming existing tools including AlphaMissense and CPT-1.

2 citations

machine learning (classical)variant effect prediction

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