John G. R. Jefferys

This study uses chemicogenetic techniques to selectively enhance inhibitory interneurons in the hippocampus, finding that PV interneurons most effectively suppress seizure activity in vitro and in vivo.

This study investigates how synaptic and non-synaptic mechanisms interact during seizure activity in rat hippocampal slices, finding that non-synaptic processes drive seizure onset while synaptic inhibition modulates event progression.