Author

Madeline L. Arnold

University of California, BerkeleyORCID 0000-0003-0130-4789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein design· 1 Approach:statistical model· 1

Frequent Co-Authors

Arik ShamsiD· 1 shared Benjamin L. Oakes· 1 shared Brett T. Staahl· 1 shared Christof FellmanniD· 1 shared David F. SavageiD· 1 shared Eva K. NicholsiD· 1 shared Hsiu‐Chun Chuang· 1 shared Jennifer A. DoudnaiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Arik ShamsORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedSep 27, 2021

Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules

Arik Shams, Sean A. Higgins, Christof Fellmann…·David F. Savage

The paper uses a genetic minimization technique to identify minimal DNA-binding modules in Cas9, showing that large domain deletions can retain function.

50 citations

experimental assayprotein design

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 9, 2020

Fetal innate immunity contributes to the induction of atypical behaviors in a mouse model of maternal immune activation

Eva K. Nichols, Hsiu‐Chun Chuang, Matthew T. Davis…·Kaoru Saijo

This study shows that TLR3-mediated maternal immune activation induces specific behavioral changes in mouse offspring through fetal innate immunity.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky