NeurosciencebioRxivPreprint
Dynamic conformational ensembles of soluble Tau encode neuronal toxicity prior to aggregation
Florian Georgescauld, Sonia Okekenwa, Tanner Boyd…·Yuyu Song
This study identifies dynamic conformational states of soluble Tau that precede aggregation and correlate with neuronal toxicity in Alzheimer's disease and related tauopathies.