Author

Preeti Iyer

AstraZeneca (Sweden)ORCID 0000-0003-0136-0123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Amir Taheri‐GhahfarokhiiD· 1 shared Anders LundiniD· 1 shared Bastian SchiffthaleriD· 1 shared Björn Magnusson· 1 shared Burcu BestasiD· 1 shared Elaine B. CadoganiD· 1 shared Johan Brengdahl· 1 shared Jonathan Sumner· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Amir Taheri‐GhahfarokhiORCID

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1 paper

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedAug 14, 2023

Simultaneous inhibition of DNA-PK and Pol{Theta} improves integration efficiency and precision of genome editing

Sandra Wimberger, Nina Akrap, Mike A. Firth…·Marcello Maresca

This study identifies AZD7648 and Pol{Theta} inhibitors as a combination (2iHDR) that enhances CRISPR-Cas9 integration efficiency and precision by targeting DNA-PK and MMEJ repair pathways.

137 citationstop 1%

CRISPR screenexperimental assay

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