Author

Isabel Fabregat

Institut d'Investigació Biomédica de BellvitgeORCID 0000-0003-0136-8440Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Josep AmengualiD· 2 shared Aashreya RavichandraiD· 1 shared Allan PavyiD· 1 shared Ángel RayaiD· 1 shared Antonella ConsiglioiD· 1 shared Carlos Andres Roldan-HernandeziD· 1 shared Cédric CoulouarniD· 1 shared Christin WeisslederiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Josep AmengualORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 10, 2025

ZEB1 regulates BCL2 in cancer-associated fibroblasts to promote cholangiocarcinoma chemoresistance to gemcitabine and cisplatin

Ester Gonzalez‐Sanchez, Marie Vallette, Aashreya Ravichandra…·Javier Vaquero

This study shows ZEB1 in cancer-associated fibroblasts regulates BCL2 to promote chemoresistance in cholangiocarcinoma, suggesting BCL2 inhibitors could enhance gemcitabine and cisplatin efficacy.

DOI 10.1101/2025.09.10.675294

humanscRNA-seq

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Cell BiologybioRxivPreprintAug 1, 2025

Astrocytic Ceruloplasmin Deficiency Triggers Iron Toxicity and Neurodegeneration in a LRRK2 Parkinson's Tri-Culture Model

Veronica Testa, Jara Montero-Muñoz, Valentina Baruffi…·Antonella Consiglio

This study identifies ceruloplasmin deficiency in mutant astrocytes as a driver of iron toxicity and neurodegeneration in a Parkinson's tri-culture model.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky