Cancer BiologyBMC BiologyPeer-reviewed
Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation.
Ben Murcott, Floris Honig, Dominic Oliver Halliwell…·Adele Murrell
This study shows that 5-hydroxymethylcytosine (5hmC) levels increase in liver metastases compared to primary colon tumors and is linked to TET2/TET3 expression and migration-related pathways.