Yangdong Wang

This paper introduces fluorescent protein-based ticker tapes (FPTT) to record transcriptional histories in single cells, demonstrating their use in tracking signaling dynamics in neurons and T-cells.

This paper develops a red fluorescent calcium indicator, SomaFRCaMPi, which improves neuronal activity imaging accuracy and scale in vivo by reducing neuropil contamination and enhancing signal-to-noise ratio.

This paper describes a method for rapidly optimizing fluorescent proteins in mammalian cells, resulting in enhanced near-infrared fluorescent proteins with improved intracellular brightness and multicolor imaging capabilities.