Kiryl D. Piatkevich

The paper introduces microProteomEx, a platform combining tissue expansion, imaging, and proteomics to achieve high-resolution spatial proteomics in hard tissues and clinical samples.

This study develops two red genetically encoded potassium indicators (RGEPOs) for real-time imaging of intracellular and extracellular potassium dynamics in various biological systems.

This paper introduces fluorescent protein-based ticker tapes (FPTT) to record transcriptional histories in single cells, demonstrating their use in tracking signaling dynamics in neurons and T-cells.

The paper introduces novel far-red fluorescent proteins for temporal domain multiplexing and super-resolution imaging, enabling subcellular structure distinction without hardware modifications.

This paper introduces two photostable voltage sensors, ElectraON and ElectraOFF, which enable longer in vivo recordings by improving photostability compared to existing GEVIs.

The paper introduces Vega, a photostable GEVI with high sensitivity and fast response, enabling high-fidelity voltage imaging in tissue and live animals.

This paper develops a red fluorescent calcium indicator, SomaFRCaMPi, which improves neuronal activity imaging accuracy and scale in vivo by reducing neuropil contamination and enhancing signal-to-noise ratio.

This study shows that modifying the optical properties of a mammalian brain can enhance deep imaging without affecting native physiology.

This paper describes a method for rapidly optimizing fluorescent proteins in mammalian cells, resulting in enhanced near-infrared fluorescent proteins with improved intracellular brightness and multicolor imaging capabilities.

This paper demonstrates whole-body expansion microscopy (ExM) for nanoscale imaging of zebrafish larvae and mouse embryos, enabling detailed visualization of anatomical structures and proteins.

The paper introduces two improved near-infrared calcium indicators for better neuronal activity imaging in vivo.

The paper develops cell body-targeted calcium indicators to improve signal fidelity in one-photon imaging of neural activity in live mice and zebrafish.

All-optical electrophysiology in awake mice reveals inhibitory microcircuit function in barrel cortex Layer 1 by combining voltage recording with optogenetic manipulation.

The paper introduces a new genetically encoded voltage indicator, SomArchon, enabling high-speed, sensitive neural activity imaging in awake mice across multiple brain regions.