Valeria Sordi

This paper develops a deep learning model to predict stem cell efficiency for beta cell differentiation using phase-contrast images, achieving high accuracy in clone classification.

The paper constructs a single-cell multiomics atlas of the human pancreas across development, health, and T2D, identifying plastic cell states and lineage trajectories.

This study shows liraglutide treatment restores glucose-stimulated insulin secretion and reduces apoptosis in WFS1 mutant iPSC-derived β cells.

This study identifies noncoding regulatory regions and their mutations in insulinomas, linking them to altered β-cell function and tumor development.

This study investigates how a WFS1 splice site mutation affects β cell apoptosis in Wolfram syndrome by analyzing alternative splicing and functional consequences in patient-derived iPSCs.