Johannes Liebig

This study uses single-cell transcriptomics to show that SARS-CoV-2 variants reshape pediatric upper-airway immunity differently from adults.

The paper constructs a single-cell multiomics atlas of the human pancreas across development, health, and T2D, identifying plastic cell states and lineage trajectories.

The paper investigates the role of Tbx1 in cardiopharyngeal mesoderm differentiation and morphogenesis, finding it stabilizes transcriptional profiles and regulates a conserved gene module.

This study shows that acute pancreatitis induces epigenetic changes in acinar cells, leading to long-term tumor predisposition through altered cell states and plasticity.