Author

Daniel R. Zollinger

Nanostring Technologies (United States)ORCID 0000-0003-0181-4228Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 3 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Assay:spatial transcriptomics· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Joseph BeechemiD· 3 shared Robin FropfiD· 3 shared Caroline B. M. PorteriD· 2 shared Devan PhillipsiD· 2 shared Domenic AbbondanzaiD· 2 shared Jason ReevesiD· 2 shared Jill McKay-Fleisch· 2 shared Joshua GouldiD· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Joseph BeechemORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 29, 2021

Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling

Stephanie M. Zimmerman, Robin Fropf, Bridget R. Kulasekara…·Joseph Beechem

Multiplexed in situ hybridization pools against every protein-coding gene let Digital Spatial Profiling read whole transcriptomes from regions of ~10-500 cells in human and mouse tissue.

60 citations

humanmouse

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 25, 2021

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

Toni Marie Delorey, Carly G.K. Ziegler, Graham Heimberg…·Alexandra–Chloé Villani

This study creates a single-cell and spatial atlas of autopsy tissues from COVID-19 patients, revealing altered cellular responses and potential therapeutic targets.

40 citations

humanscRNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintAug 25, 2020

Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment

William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo…·Aviv Regev

This study uses single-nucleus and spatial transcriptomics to analyze pancreatic cancer before and after neoadjuvant treatment, revealing changes in cell states and immune infiltration that may inform therapy.

33 citations

humansnRNA-seq

𝕏 PostBluesky

PathologybioRxivPreprintFeb 26, 2019

High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methods

Christopher R. Merritt, Giang T. Ong, Sarah Church…·Joseph M. Beechem

This paper introduces Digital Spatial Profiling (DSP), a method for high-plex spatial analysis of proteins and RNA in tissue, and demonstrates its application in studying immune and cancer microenvironments.

DOI 10.1101/559021

humanprotein structure

𝕏 PostBluesky