Author

Cagla Akay

University of PennsylvaniaORCID 0000-0003-0199-3836Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Kelly L. Jordan‐SciuttoiD· 2 shared Elena Alvarez-PerieliD· 1 shared Ernesto Baçi· 1 shared James GesualdiiD· 1 shared Jayden Cyrus· 1 shared Jude Prah· 1 shared Peter J. GaskilliD· 1 shared Sarah E. Bond NewtoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Kelly L. Jordan‐SciuttoORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 30, 2026

Genetic variation in EIF2AK3 alters astrocyte-dependent stress tolerance in neurons

Shivesh Ghura, Elena Alvarez-Periel, Sarah E. Bond Newton…·Kelly L. Jordan‐Sciutto

The paper investigates how genetic variation in EIF2AK3 (PERK) affects astrocyte-dependent stress tolerance in neurons, showing PERK-B haplotype leads to altered stress response kinetics and reduced stress tolerance.

DOI 10.64898/2026.09.29.755429

mouseexperimental assay

𝕏 PostBluesky

ImmunologyScientific ReportsPeer-reviewedMar 11, 2026

Neuroinflammatory crosstalk between microglia and astrocytes increases viral replication in an iPSC-derived model of CNS HIV infection

James Gesualdi, Jude Prah, Shiden Solomon…·Kelly L. Jordan‐Sciutto

This study shows that neuroinflammatory interactions between microglia and astrocytes in an iPSC model enhance HIV replication through TNF and NF-kB pathways.

3 citationstop 2%

humanexperimental assay

𝕏 PostBluesky