Kelly L. Jordan‐Sciutto

The paper investigates how genetic variation in EIF2AK3 (PERK) affects astrocyte-dependent stress tolerance in neurons, showing PERK-B haplotype leads to altered stress response kinetics and reduced stress tolerance.

This study shows TRPML1 regulates oligodendrocyte morphology and myelination through actin dynamics and calcium signaling during differentiation.

This study shows that neuroinflammatory interactions between microglia and astrocytes in an iPSC model enhance HIV replication through TNF and NF-kB pathways.

This study shows that bictegravir inhibits oligodendrocyte maturation by causing lysosomal de-acidification, which can be reversed by activating TRPML1.