Author

James Gesualdi

University of PennsylvaniaORCID 0000-0002-7846-2761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adriana Hernandez Vásquez· 1 shared Alexis Mary CrockettiD· 1 shared Angela Nicole ViaeneiD· 1 shared Cagla AkayiD· 1 shared Caroline Canning· 1 shared Donna M. McDonald‐McGinniD· 1 shared Elaine H. ZackaiiD· 1 shared Ernesto Baçi· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Adriana Hernandez Vásquez

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2 papers

Recent·Most cited

ImmunologyScientific ReportsPeer-reviewedMar 11, 2026

Neuroinflammatory crosstalk between microglia and astrocytes increases viral replication in an iPSC-derived model of CNS HIV infection

James Gesualdi, Jude Prah, Shiden Solomon…·Kelly L. Jordan‐Sciutto

This study shows that neuroinflammatory interactions between microglia and astrocytes in an iPSC model enhance HIV replication through TNF and NF-kB pathways.

3 citationstop 2%

humanexperimental assay

𝕏 PostBluesky

NeuroscienceBrainPeer-reviewedMar 2, 2021

Disruption of the blood brain barrier in 22q11.2 deletion syndrome

Alexis Mary Crockett, Sean K. Ryan, Adriana Hernandez Vásquez…·Jorge Ivan Alvarez

This study shows that the blood brain barrier in 22q11.2 deletion syndrome is compromised, leading to increased neuroinflammation and potential risk for neuropsychiatric disorders.

65 citations

𝕏 PostBluesky