Makenzie R. Norris

Neuropathic injury drives a generalized negative affective state in mice

This study shows that spared nerve injury in mice does not significantly affect negative affective behaviors in short-term tests but reveals reduced motivation for food rewards in long-term testing.

Mu opioid receptors gate the locus coeruleus pain generator

This study identifies mu opioid receptors in the locus coeruleus as critical regulators of pain, showing they gate the LC's role as a pain generator through bidirectional modulation of hyperalgesia.

Spared nerve injury causes motor phenotypes unrelated to pain in mice

The paper uses DeepLabCut to analyze limb positioning in mice after spared nerve injury (SNI) and finds motor phenotypes not related to pain.

Sex differences in fear regulation and reward seeking behaviors in a fear-safety-reward discrimination task

This study investigates sex differences in fear, safety, and reward regulation in rats, finding females exhibit distinct behavioral responses compared to males in a discrimination task.