Kathleen K.A. Cho

This study shows that circuit inhibition in the prefrontal cortex enables dynamic reorganization of task encoding, supporting cognitive flexibility by allowing rapid shifts in rule representations during learning.

The paper identifies long-range inhibitory projections from prefrontal parvalbumin neurons that synchronize neural activity and enable behavioral strategy updates during cognitive tasks.

This study shows that gamma synchrony between parvalbumin interneurons supports behavioral adaptation by enabling mice to update cue-reward associations.