Author

Thomas Bradley

University of CambridgeORCID 0000-0003-0218-5021Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Florian M. MarkowetziD· 2 shared James D. BrentoniD· 2 shared Akane Ota· 1 shared Amy E CulleniD· 1 shared Anna PiskorziD· 1 shared Carolin M. SaueriD· 1 shared Dominique‐Laurent CouturieriD· 1 shared Geoff MacintyreiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Florian M. MarkowetzORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 30, 2026

scUnique: Measuring Ongoing Chromosomal Instability

Michael P Schneider, Shadi Darvish Shafighi, Amy E Cullen…·Florian M. Markowetz

scUnique measures ongoing chromosomal instability from single-cell whole genome sequencing data by identifying recent copy number aberrations in phylogenetic trees.

1 citation

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJul 19, 2021

Absolute copy number fitting from shallow whole genome sequencing data

Carolin M. Sauer, Matthew Eldridge, Maria Vias…·James D. Brenton

The paper evaluates tools for estimating absolute copy numbers from shallow whole genome sequencing data and introduces an improved tool called Rascal.

19 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky

BioinformaticsBioinformaticsPeer-reviewedJan 9, 2020

FilTar: Using RNA-Seq data to improve microRNA target prediction accuracy in animals

Thomas Bradley, Simon Moxon

FilTar improves miRNA target prediction accuracy in animals by using RNA-Seq data to filter non-expressed transcripts and refine 3UTR annotations.

13 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky