Author

Saima Noor Hassan

Centre Hospitalier de l’Université de MontréalORCID 0000-0003-0232-2807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Mallory I. Frederick· 2 shared Anna ClouveliD· 1 shared Djihane Abdesselam· 1 shared Elicia Fyle· 1 shared Gerardo FerbeyreiD· 1 shared Kenan AlossiD· 1 shared Nicolas Pouderous· 1 shared Qi YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Mallory I. Frederick

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Targeting ribosome biogenesis sensitizes PARPi-resistant triple-negative breast cancer

Mallory I. Frederick, Nicolas Pouderous, Kenan Aloss, Qi Yang, Gerardo Ferbeyre, Saima Noor Hassan

This study shows that combining PARPi with ribosome biogenesis inhibitors sensitizes PARPi-resistant triple-negative breast cancer cells and identifies ribosome biogenesis as a therapeutic target.

bioRxiv · Oct 9, 2026 · PreprintCancer Biology

Targeting FEN1 to enhance efficacy of PARP inhibition in triple-negative breast cancer

Mallory I. Frederick, Elicia Fyle, Anna Clouvel, Djihane Abdesselam, Saima Noor Hassan

This study identifies FEN1 as a target to enhance PARP inhibitor efficacy in PARPi-resistant triple-negative breast cancer cell lines and organoids.

Translational Oncology · Mar 6, 2025Peer-reviewedCancer Biology