NeuroscienceCell Death and DiseasePeer-reviewed
Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer's disease mouse model: a role for ER-mitochondria interaction.
Laura Tapella, Giulia Dematteis, Marianna Moro…·Dmitry Lim
This study shows that in Alzheimer's disease astrocytes, protein synthesis is impaired through PERK-independent p-eIF2 activation, linked to altered ER-mitochondria interactions, affecting homeostatic functions.
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