Author

Elisa Tonelli

Università degli Studi del Piemonte Orientale “Amedeo Avogadro”ORCID 0009-0000-1868-6707Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Armando A. GenazzaniiD· 2 shared Dmitry LimiD· 2 shared Giulia DematteisiD· 2 shared Laura TapellaiD· 2 shared Mariagrazia GrilliiD· 2 shared Marisa BriniiD· 2 shared Tito CalíiD· 2 shared Adele Ariotti· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

Armando A. GenazzaniORCID

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2 papers

Recent·Most cited

Cell BiologyCommunications BiologyPeer-reviewedOct 10, 2024

ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism.

Giulia Dematteis, Laura Tapella, Claudio Casali…·Dmitry Lim

The paper shows that an optimal ER-mitochondria distance of ~20 nm is critical for efficient Ca2+ transfer and mitochondrial oxidative metabolism, with reduced distances observed in Parkinson's disease astrocytes.

75 citationstop 1%

humanproteomics

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NeuroscienceCell Death and DiseasePeer-reviewedOct 18, 2022

Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer's disease mouse model: a role for ER-mitochondria interaction.

Laura Tapella, Giulia Dematteis, Marianna Moro…·Dmitry Lim

This study shows that in Alzheimer's disease astrocytes, protein synthesis is impaired through PERK-independent p-eIF2 activation, linked to altered ER-mitochondria interactions, affecting homeostatic functions.

34 citationstop 5%

mouseproteomics

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