Author

Andrew Wallace

GenentechORCID 0000-0003-0235-4737Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Andrew Wallace1 paper · University of California, Santa Cruz

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Darya Yu. OrlovaiD· 1 shared Gergő NikolényiiD· 1 shared Kiran MukhyalaiD· 1 shared Martin CulkaiD· 1 shared Mohammed AlQuraishiiD· 1 shared Nicolas LounsburyiD· 1 shared Santrupti NerliiD· 1 shared William John ThriftiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

Darya Yu. OrlovaORCID

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1 paper

Recent·Most cited

ImmunologyCell SystemsPeer-reviewedAug 13, 2026

Predicting specificity of TCR-pMHC interactions using machine learning and biophysical models

Martin Culka, Nicolas Lounsbury, William John Thrift…·Mohammed AlQuraishi

This study evaluates ML and biophysical models for predicting TCR-pMHC specificity, showing ML struggles with novel peptides while biophysical methods excel but underperform on known ones, leading to a hybrid model with improved performance.

8 citationstop 2%

humanproteomics

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