Morgan A. Sammons

The paper investigates the differential transcriptional activity of ΔNp63β compared to ΔNp63α, showing unique gene regulation and histone modification patterns.

The paper introduces p53motifDB, a database integrating genomic data and p53 binding motifs to help generate hypotheses about p53 activity in the human genome.

The paper investigates how DNA sequence and cellular context influence p63-mediated transcription through MPRA in various contexts, finding that p63RE-bound elements show varied activity linked to GC content and p53 binding.

This study identifies shared gene targets regulated by p53 and ATF4, revealing convergent mechanisms in metabolic and pro-apoptotic gene control.

The paper investigates how local transcription factors influence p53-bound cis-regulatory elements, showing that co-regulatory factors and sequence context affect CRE activity and gene expression.

This study shows that Smad4 signaling is essential for the development, function, and circuit formation of basal vomeronasal sensory neurons.

The paper shows that p53's transcriptional activity varies by cell type and is influenced by p63's role in enhancer binding and maintenance in epithelial cells.

The paper compares genotoxic and non-genotoxic p53 activation in human fibroblasts, showing similar genome-wide binding and chromatin changes but distinct inflammatory gene expression patterns.

This study shows that AP-2ε maintains basal vomeronasal sensory neuron identity by preventing apical gene expression and highlights their differentiation plasticity.