Author

Povilas Kavaliauskas

Lithuanian University of Health SciencesORCID 0000-0003-0237-9088Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

Birutė GrybaitėiD· 2 shared Vidmantas PetraitisiD· 2 shared Vytautas MickevičiusiD· 2 shared Andrew Jesse GarciaiD· 1 shared Antonella PasquatoiD· 1 shared Benedetta FongaroiD· 1 shared Birutė Sapijanskaitė-BanevičiD· 1 shared Donatella TondiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Birutė GrybaitėORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Identification and characterization of a small-molecule inhibitor of the Pseudomonas aeruginosa SOS response

Filippo Vascon, Benedetta Fongaro, Vytautas Mickevičius, Antonella Pasquato, Birutė Grybaitė, Vidmantas Petraitis, Rahma Ben Abderrazek, Patrizia Polverino de Laureto, Donatella Tondi, Povilas Kavaliauskas, Laura Cendron

This study identifies and characterizes a small-molecule inhibitor, A12, of the SOS response in Pseudomonas aeruginosa, showing it binds RecA and LexA and forms disulfide bonds, with potential for anti-SOS compound development.

ACS Infectious Diseases · Nov 7, 2025Peer-reviewedBiochemistry

Synthesis of Novel N-Substituted β-Amino Acid Derivatives Bearing 2-Hydroxyphenyl Moieties as Promising Antimicrobial Candidates Targeting Multidrug-Resistant Gram-Positive Pathogens

Povilas Kavaliauskas, Birutė Grybaitė, Birutė Sapijanskaitė-Banevič, Rūta Petraitienė, Ramunė Grigalevičiūtė, Andrew Jesse Garcia, Ethan Naing, Vytautas Mickevičius, Sergey Belyakov, Vidmantas Petraitis

This study synthesizes and tests new N-substituted β-amino acid derivatives with 2-hydroxyphenyl groups against multidrug-resistant Gram-positive bacteria, finding some compounds show promising antimicrobial activity.

PLoS ONE · Jun 12, 2025Peer-reviewedMicrobiology