Dynamic Antigen Expression and Intrinsic CTL Resistance in HIV Reservoir Clones
Isabella A. T. M. Ferreira, Alberto Herrera, Tan Thinh Huynh, Nathan L. Board, Emily Stone, Noemi Linden, Yanqin Ren, Cíntia Bittar, Virender Kumar Pal, Shane Vedova, Ethan Naing, Parul Sinha, Ali Danesh, Cristian Ovies, Fitty L Liu, , Richard Brad Jones
This study characterizes HIV reservoir clones and shows they can be culled by sustained CTL pressure, with some displaying intrinsic resistance linked to low oxidative stress.
bioRxiv · Feb 23, 2026 · PreprintImmunology