Author

Agnieszka Chryplewicz

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-0253-1166Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Allen C. ZhuiD· 1 shared Anuradha GopalaniD· 1 shared Brett Stewart CarveriD· 1 shared Charles L. SawyersiD· 1 shared Chuan HeiD· 1 shared Dana Pe’eriD· 1 shared Dario F. De JesusiD· 1 shared Decheng ReniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Allen C. ZhuORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 31, 2026

IL-1β/IL-6 signaling circuit in the tumor microenvironment drives prostate cancer development

Young Sun Lee, Jimmy L. Zhao, Agnieszka Chryplewicz…·Charles L. Sawyers

This study identifies an IL-1β/IL-6 signaling circuit in the tumor microenvironment that drives prostate cancer progression from pre-invasive to invasive stages.

DOI 10.64898/2026.07.30.741572

mousebulk RNA-seq

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BioinformaticsGenome biologyPeer-reviewedDec 1, 2019

RADAR: Differential analysis of MeRIP-seq data with a random effect model

Zijie Scott Zhang, Qi Zhang, Mark A. Eckert…·Mengjie Chen

RADAR is a tool for differential methylation analysis of MeRIP-seq data, showing improved accuracy and reproducibility compared to existing methods.

99 citationstop 4%

DNA methylationstatistical model

𝕏 PostBluesky