Zijie Scott Zhang

This study generates 10-gene-edited pigs that reduce immune rejection and zoonotic risks for xenotransplantation, showing improved survival in non-human primate recipients.

Puzzle Hi-C improves chromosome-scale genome assembly by reducing scaffolding interference through a triangle region strategy and dynamic window expansion.

This study shows that m6A methylation, regulated by METTL3, controls the innate immune response in β-cells during T1D onset by modulating OAS mRNA stability.

RADAR is a tool for differential methylation analysis of MeRIP-seq data, showing improved accuracy and reproducibility compared to existing methods.

This paper introduces an antibody-independent method for single-base m6A mapping, showing high reliability and conservation across species.

The paper reduces mitochondrial reads in ATAC-seq using CRISPR/Cas9 and a modified protocol, improving peak calling and reducing costs.