Author

Heleen H. T. Middelkamp

University of TwenteORCID 0000-0003-0267-8811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert van den BergiD· 1 shared Andries D. van der MeeriD· 1 shared Cisca WijmengaiD· 1 shared Iris H. JonkersiD· 1 shared Kieu T. T. LeiD· 1 shared Leo A. B. JoosteniD· 1 shared Mihai Gheorghe NeteaiD· 1 shared Nick KeuriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Albert van den BergORCID

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1 paper

Recent·Most cited

Molecular BiologyMolecular OmicsPeer-reviewedOct 14, 2025

Cytokine-induced memory-like responses in endothelial cells link chronic inflammation to vascular disease risk

Kieu T. T. Le, Nick Keur, Heleen H. T. Middelkamp…·Vinod Kumar

This study shows that repeated cytokine exposure in endothelial cells induces memory-like responses, linking chronic inflammation to vascular disease risk through persistent transcriptional and epigenetic changes.

13 citationstop 4%

humanbulk RNA-seq

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