Rong Li

This study identifies phenotype-cloud transitions as an organizational feature of cancer progression and therapeutic adaptation, showing how tumours reorganize phenotypic states during progression and treatment.

This paper maps breast cancer evolution in situ using spatial transcriptomics and other data to show that tumor progression is driven by spatially coherent fronts rather than predefined clonal branches.

CellDiffusion improves scRNA-seq data integration by accurately inferring cell-cell associations and correcting batch effects across diverse datasets.

GametesOmics integrates multi-omics data from human and mouse gametogenesis to provide tools for analyzing gene expression, DNA methylation, and chromatin accessibility.

This paper describes a method to generate blastocyst-like structures from human pluripotent stem cells and shows they resemble blastocysts in morphology and transcriptome.

This study investigates the epigenetic effects of prenatal testosterone transfer between opposite-sex twins using DNA methylation and histone modification data, finding distinct epigenetic signatures linked to cognition, nervous system, and immune responses.

This study profiles the transcriptomes of human oocytes and granulosa cells across folliculogenesis stages, identifying stage-specific genes, cell interactions, and differences from mouse oocytes.