Author

Yuchen Liu

Harvard UniversityORCID 0000-0001-8922-9976Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yuchen Liu10 papers · Chinese Academy of Medical Sciences & Peking Union Medical College

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:batch correction / integration· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:contrastive learning· 1

Frequent Co-Authors

Yingzi YangiD· 2 shared Andrew Graham CoxiD· 1 shared Anthony P. KaramalakisiD· 1 shared Chao ZhangiD· 1 shared Dong He XuiD· 1 shared Heng PaniD· 1 shared Jay R. BlackiD· 1 shared Jin JiangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

Yingzi YangORCID

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3 papers

Recent·Most cited

YAP disrupts bile acid homeostasis to drive cancer-associated cachexia

Madeline Webb, Mikaela Wong, Anthony P. Karamalakis, Yuchen Liu, Kimberley Jane Evason, Kira Sun, Kristin Brown, Jay R. Black, Yingzi Yang, Andrew Graham Cox

This study identifies YAP's role in disrupting bile acid homeostasis to drive cachexia in zebrafish, showing that promoting bile acid excretion can alleviate the syndrome.

bioRxiv · Feb 3, 2026 · PreprintCancer Biology

The Hippo pathway effector YAP inhibits NF-kB signaling and ccRCC growth by opposing ZHX2

Xu Li, Yong Suk Cho, Yuhong Han, Mengmeng Zhou, Yuchen Liu, Yingzi Yang, Shu Zhuo, Jin Jiang

This study shows YAP inhibits NF-κB signaling and ccRCC growth by blocking ZHX2, a co-factor of NF-κB, and competes with ZHX2 for binding to p65.

Journal of Biological Chemistry · Mar 20, 2025Peer-reviewedCancer Biology

CellDiffusion: Enhancing scRNA-seq data integration with accurate inference of cell-cell association

Yuchen Liu, Ziying Huang, Simon Liang Lu, Lei Jiang, Zedong Lin, Jou-Hsuan Lee, Vijaya B. Kolachalama, Rong Li, Dong He Xu, Juexin Wang, Heng Pan, Chao Zhang

CellDiffusion improves scRNA-seq data integration by accurately inferring cell-cell associations and correcting batch effects across diverse datasets.

bioRxiv · Jan 28, 2024 · PreprintBioinformatics