Author

Conor J. Crawford

Max Planck Institute of Colloids and InterfacesORCID 0000-0002-1314-1019Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:metagenomics· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alan CartmelliD· 2 shared Charles W.E. TomlinsoniD· 2 shared Edwin Alexander YatesiD· 2 shared Spencer John WilliamsiD· 2 shared Stefano ElliiD· 2 shared Zongjia CheniD· 2 shared Adam DowleiD· 1 shared Ana Sofia LuisiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersBiochemistry

Alan CartmellORCID

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Author profile →

3 papers

Recent·Most cited

Structural basis for covalent inhibition of sulfatases by sulfamate warheads

Charles W.E. Tomlinson, Stefano Elli, Morgan E Batiste-Simms, Zongjia Chen, Chris Taylor, Adam Dowle, Edwin Alexander Yates, Marc Nazaré, Martin A. Fascione, Lianne I. Willems, Spencer John Williams, Conor J. Crawford, Alan Cartmell

This paper investigates why aryl sulfatases are inhibited by sulfamate warheads while carbohydrate sulfatases are not, using structural and computational analyses.

bioRxiv · Aug 28, 2026 · PreprintBiochemistry

Sulfated mannan helps diatoms domesticate their microbiome

Joris Krull, Conor J. Crawford, Chandni Sidhu, Vipul Solanki, Margot Bligh, Leonard Rößler, R. K. Singh, Guoyin Huang, Craig S. Robb, Hanno Teeling, Peter H. Seeberger, Thomas Schweder, Jan‐Hendrik Hehemann

This paper shows diatoms exude sulfated mannan to selectively nourish bacteria, shaping their microbiome to enhance productivity and carbon cycling.

Microbiome · Mar 26, 2026Peer-reviewedEcology

Arylsulfamates inhibit colonic Bacteroidota growth through a sulfatase-independent mechanism

Conor J. Crawford, Charles W.E. Tomlinson, Christian Gunawan, Zongjia Chen, Dominic P. Byrne, Cosette Darby, Martina Conti, Tony R. Larson, Ana Sofia Luis, Stefano Elli, Edwin Alexander Yates, David N. Bolam, Sjoerd van der Post, Spencer John Williams, Alan Cartmell

The paper shows arylsulfamates inhibit Bacteroides growth on sulfated glycans via a lipid kinase, not carbohydrate sulfatases, and identifies resistance mechanisms.

Proceedings of the National Academy of Sciences · Jul 10, 2025Peer-reviewedBiochemistry