Author

Louise Brennan

University of LiverpoolORCID 0000-0003-0324-2665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew D. Bates· 2 shared Conor J. FawcettiD· 2 shared Urszula Lucja McClurgiD· 2 shared Aina G Ginesta· 1 shared Amanda Thomaz· 1 shared Andrew B. FieldingiD· 1 shared Asma SaifudeeniD· 1 shared Beth HammondiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Andrew D. Bates

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 11, 2026

The meiotic synaptonemal complex is assembled from independently regulated gene programmes

Louise Brennan, Conor J. Fawcett, Iong F Sou…·Urszula Lucja McClurg

The paper shows that SC genes are independently regulated rather than coordinated, with implications for cancer and somatic expression.

DOI 10.64898/2026.09.09.750351

𝕏 PostBluesky

Cancer BiologybioRxivSep 18, 2025

Moonlighting Role of Meiotic SYCP1 in Breast Cancer: A Chromatin-Bound Regulator of DNA Repair, Transcription, and Drug Resistance

Urszula Lucja McClurg, Wee-Wei Tee, Owen Richard Davies…·Andrew B. Fielding

This study identifies SYCP1 as a chromatin-bound regulator in breast cancer that promotes DNA repair, transcription, and drug resistance, with clinical implications for prognosis and therapy.

DOI 10.1126/sciadv.aea2067

humanproteomics

𝕏 PostBluesky