Jordan M. Valone

The paper assesses regulatory activity of cortical structure-associated variants using MPRA in human neural progenitor cells, identifying 918 variants with regulatory potential and showing condition-dependent effects.

The paper exposes human neural progenitors to valproic acid and lithium, identifying gene by treatment interactions linked to psychiatric disorder risk and folate metabolism.

This paper introduces a method to classify gene-by-treatment interactions using Bayesian model selection and applies it to molecular count phenotypes with a software package.

The paper identifies cell-type-specific genetic regulation of RNA-editing and alternative polyadenylation in human neural progenitors and neurons, linking these to brain-related traits.

The paper identifies context-specific genetic effects on gene regulation in neural progenitors by stimulating the Wnt pathway and analyzing chromatin accessibility and gene expression.