Justin M. Wolter

This study shows that sleeve gastrectomy improves metabolic health, cognition, and Alzheimer's pathology in 3xTg-AD mice by modulating autophagy and insulin signaling.

The paper exposes human neural progenitors to valproic acid and lithium, identifying gene by treatment interactions linked to psychiatric disorder risk and folate metabolism.

The paper identifies context-specific genetic effects on gene regulation in neural progenitors by stimulating the Wnt pathway and analyzing chromatin accessibility and gene expression.

The paper identifies miRNA-eQTLs in human neocortical tissue, linking miR-4707-3p expression to brain size and educational attainment through colocalization with GWAS data.

The paper identifies a genetic locus on chr3p21.1 associated with lithium-induced neural progenitor proliferation and links it to bipolar disorder risk through the gene GNL3.

The paper identifies cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation and links these to regulatory mechanisms of neuropsychiatric disorder risk variants.

The paper screens a chemical library to identify environmental chemicals that modulate Wnt signaling, finding diethanolamine as a stimulator with potential for prenatal exposure.