Cancer BiologybioRxivPreprint
Skeletal Metastasis of Prostate Cancer Is Augmented by Activation of EphA2 Noncanonical Signaling and Ligand-Deficient Bone Microenvironment
Ryan Lingerak, Aaron P. Petty, Xiaojun Shi…·Bingcheng Wang
This study shows EphA2 overexpression and loss of its ligands in prostate cancer promote bone metastasis through noncanonical signaling in a ligand-deficient bone microenvironment.
DOI 10.1101/2024.09.25.615079