Genetic & Genomic MedicinemedRxivPreprint
Rare coding variation implicates thirteen genes in bipolar disorder across 232,536 individuals from global populations
DOI 10.64898/2026.09.30.26364416
Author
Po‐Hsiu Kuo
National Taiwan UniversityORCID 0000-0003-0365-3587Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2017-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 35 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 shared papersGenetic & Genomic Medicine
Yi‐Hsiang HsuORCID
Mutual co-authors in cluster
6 papers
Recent·Most cited
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Analysis across Taiwan Biobank, Biobank Japan and UK Biobank identifies hundreds of novel loci for 36 quantitative traits
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Polygenic scores for major depressive disorder and depressive symptoms predict response to lithium in patients with bipolar disorder
Azmeraw T. Amare, Klaus Oliver Schubert, Liping Hou…·Mario Maj
The paper shows that polygenic scores for depression traits predict lithium response in bipolar disorder patients, with lower genetic load linked to better treatment outcomes.
2 citations - GeneticsbioRxivPreprint
High genetic loading for schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis
Azmeraw T. Amare, Klaus Oliver Schubert, Liping Hou…·Gustavo Turecki
This study finds that a higher genetic risk for schizophrenia is linked to poorer lithium response in bipolar disorder patients, suggesting potential for personalized treatment strategies.
DOI 10.1101/209270