Iestyn Whitehouse

This paper introduces CAD-C, a chromatin-conformation capture method that enables high-resolution detection of sister-chromatid interactions and centromere pairing.

This paper introduces a proximity-tagging method called PCP to map chromatin architecture in yeast, revealing nucleosome organization and long-range interactions.

The paper develops Replicon-seq to map replisome positions and finds sister replisomes progress consistently but function autonomously, with Rrm3 aiding in overcoming obstacles and termination.

The paper investigates chromatin states and transcription dynamics in C. elegans embryos, finding persistent active histone marks and widespread polycistronic transcription.