Mark Y. Chan

This study compares two myocardial infarction models, showing the intact-chest model better reflects human immune responses and identifies immature neutrophils as contributors to cardiac dysfunction.

MRMhub automates processing of large-scale targeted metabolomics data, offering scalability and quality control tools, and is validated on lipidomics datasets.

This study identifies rs6903956 as a CAD risk variant that regulates endothelial dysfunction through PHACTR1 and EDN1 expression via HOXA4 and MEIS1 binding.